Urban and regional economies are closely related to international trade and labor markets. We analyze the factors of sustainable growth of cities and regions in the progress of globalization and the service economy with an aging society. We also investigate how different income classes and races are spatially distributed based on the spatial economic approach and analyze the factors of intercity and intracity economic differentials. Combined with economic geography, trade theory, transport economics, labor economics, and development economics, and developing new research areas, we aim to derive useful economic policy implications from welfare economic and social points of view.