为预防先天性梅毒呼吁尽早提交妊娠申报:根据随机提供信息实验的验证

作者 畠山树辉凪(大阪大学)、中山一世(大阪大学)、大竹文雄(教职研究员)
发表日期/编号 2026年11月 26-J-048
研究课题 为实现真正发挥作用的循证决策(EBPM)的综合研究
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概要

Syphilis is resurging in many countries, including high-income countries, making congenital syphilis a public health concern. Most cases are preventable through early access to maternal health services, highlighting the importance of reaching those likely to delay obtaining such access. We construct a risk score based on actual pregnancy notification submission behavior of individuals who had experienced childbirth and extrapolated it to participants in a randomized information experiment to examine effects of information provision according to predicted risk of delayed submission. A congenital syphilis prevention message produced the largest average effect, whereas a message explaining treatment became more effective as delay risk increased, with the treatment-message intervention yielding larger effects in the highest-risk group. These findings highlight the importance of considering effects on high-risk groups alongside average effects when designing information interventions. Using risk predicted from past behavior to assess treatment effect heterogeneity may also inform other policy settings where target groups are small and difficult to identify in advance.